Azure PowerShell and Azure CLI both support automation and infrastructure management in Azure, but they differ in style and typical usage. Azure PowerShell is object-based and built on PowerShell, returning structured .NET objects that make complex scripting and advanced automation easier, especially in Windows-centric enterprise environments. It integrates well with existing PowerShell workflows and is often preferred for detailed administrative tasks. Azure CLI, in contrast, is cross-platform and command-based, returning JSON output that works naturally with Bash scripting and CI/CD pipelines, making it popular in cloud-native and DevOps environments. In practice, Azure CLI is commonly chosen for lightweight, portable automation across different operating systems, while Azure PowerShell is favored when deeper scripting flexibility and integration within Microsoft ecosystems are required.