Block Blobs, Page Blobs, and Append Blobs in Azure Blob Storage differ mainly in how they store and handle data. Block Blobs are optimized for storing text or binary files like documents, images, and videos, and they support efficient uploads and updates through blocks, making them ideal for general-purpose storage. Page Blobs are designed for random read/write operations and are commonly used for virtual hard disks (VHDs) in Azure virtual machines, where frequent updates to small data ranges are required. Append Blobs are specialized for append-only operations, making them suitable for logging scenarios where new data is continuously added without modifying existing content. In my opinion, the most important factor when choosing among them is use case suitability because each blob type is specifically optimized for a particular workload, and selecting the right one ensures better performance, cost efficiency, and proper handling of data access patterns.