Configuring AppDynamics agents effectively is essential for accurate monitoring and optimal performance. Start by ensuring that each agent version matches the Controller version to avoid compatibility issues. Enable only the required instrumentation levels to reduce overhead and prevent excessive data collection. Carefully configure naming rules so business transactions are logically grouped and easy to analyze. Use environment-specific configuration files to maintain consistency across development, staging, and production environments. It is also important to define health rules, thresholds, and custom metrics that align with your application’s performance goals. Regularly review agent logs to detect configuration errors early, and make use of secure credentials and encrypted communication to protect sensitive data. Following these practices ensures reliable data collection, lower operational risk, and improved visibility across your application ecosystem.